Machine-induced vibrations represent, for several reasons, a crucial design issue for industrial buildings. At the early design stage, special attention is thus required for the static and dynamic performance assessment of the load-bearing members, given that they should optimally withstand ordinary design loads but also potentially severe machinery operations. The knowledge and reliable description of the input vibration source is a key step, similarly to a reliable description of the structural system, to verify. However, such a kind of detailing is often unavailable and results in a series of simplified calculation assumptions. In this paper, a case-study eyewear factory built in 2019 is investigated. Its layout takes the form of a two-story, two-span (2 × 14.6 m) precast concrete frame (poor customer/designer communication on the final equipment resulted in various non-isolated computer numerical control (CNC) vertical machines mounted on the inter-story floor, that started to suffer from pronounced resonance issues. Following past experience, this paper investigates the validity of a coupled experimental–numerical method that could be used for efficient assessment predictive studies. Based on on-site experiments with Micro Electro-Mechanical Systems (MEMS) accelerometers mounted on the floor and on the machine (spindle included), the most unfavorable machine-induced vibration sources and operational conditions are first characterized. The experimental outcomes are thus used to derive a synthetized signal that is integrated in efficient one-bay finite element (FE) numerical model of the floor, in which the machine–structure interaction can be taken into account. The predictability of marked resonance issues is thus emphasized, with a focus on potential and possible limits of FE methods characterized by an increasing level of detailing and computational cost.
