ATTI DELLA SOCIETÀ DEI NATURALISTI E MATEMATICI DI MODENA
Abstract
If tha frequencies of the standard blood groups A, B, AB, 0 are known in a human population, then under the assmptions of the Hardy-Weinberg equilibrium, a direct nonlinear least squares algorithm on a computer algebra system returns the estimates for the A, B, 0 alleles frequencies. This algorithm is more informative than the classical EM (Expectation-Maximization).