Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson’s
tumor, is a rare, generally considered a non neoplastic vascular lesion, caused by an abnormal
endovascular proliferation of endothelial cells.
We describe, as far as we know, the first case of this lesion, localized at the origin of the
internal carotid artery, which was responsible for an ischemic stroke. Although this entity is very
rare, it is important for the clinician to become familiar with this lesion, since the complete
removal of the lesion is the only treatment of choice. A partial removal may lead to further
clinical events.