Significant deviations from the standard model are observed in semileptonic charged and neutral-current B decays, the muon magnetic moment, and the extraction of the Cabibbo angle. We propose that these deviations point towards a coherent pattern of new physics effects induced by two scalar mediators, a leptoquark S-1 and a charged singlet phi(+). While S-1 can provide solutions to charged-current B decays and the muon magnetic moment, and phi(+) can accommodate the Cabibbo-angle anomaly independently, their one-loop level synergy can also address neutral-current B decays. This framework provides the most minimal explanation to the above-mentioned anomalies, while being consistent with all other phenomenological constraints.
