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Molecular basis of inherited thrombocytopenias

SAVOIA, ANNA
2016
  • journal article

Periodico
CLINICAL GENETICS
Abstract
Inherited thrombocytopenias (IT) are a heterogeneous group of diseases caused by at least 20 different genes. At present, these genes account for approximately 50% of cases, suggesting that novel genes have yet to be identified for a comprehensive understanding of platelet biogenesis defects. This review provides an update of ITs focusing on the molecular basis and potential pathogenic mechanisms affecting megakaryopoiesis and platelet production.
DOI
10.1111/cge.12607
WOS
WOS:000368806900003
Archivio
http://hdl.handle.net/11368/2841118
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84964253123
http://onlinelibrary.wiley.com/doi/10.1111/cge.12607/abstract;jsessionid=6F41BD65F22267EF0C85DE2447CBE9A3.f03t04
Diritti
open access
FVG url
https://arts.units.it/request-item?handle=11368/2841118
Soggetti
  • inherited thrombocyto...

  • megakaryocytopoiesi

  • molecular basi

  • platelet biogenesis

Web of Science© citazioni
15
Data di acquisizione
Mar 14, 2024
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