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Post-Lockdown Abatement of COVID-19 by Fast Periodic Switching

M. Bin
•
P. Y. K. Cheung
•
E. Crisostomi
altro
L. Stone
2021
  • journal article

Periodico
PLOS COMPUTATIONAL BIOLOGY
Abstract
COVID-19 abatement strategies have risks and uncertainties which could lead to repeating waves of infection. We show—as proof of concept grounded on rigorous mathematical evidence— that periodic, high-frequency alternation of into, and out-of, lockdown effectively mitigates second-wave effects, while allowing continued, albeit reduced, economic activity. Periodicity confers (i) predictability, which is essential for economic sustainability, and (ii) robustness, since lockdown periods are not activated by uncertain measurements over short time scales. In turn—while not eliminating the virus—this fast switching policy is sustainable over time, and it mitigates the infection until a vaccine or treatment becomes available, while alleviating the social costs associated with long lockdowns. Typically, the policy might be in the form of 1-day of work followed by 6-days of lockdown every week (or perhaps 2 days working, 5 days off) and it can be modified at a slow-rate based on measurements filtered over longer time scales. Our results highlight the potential efficacy of high frequency switching interventions in post lockdown mitigation. All code is available on Github at https:// github.com/V4p1d/FPSP_Covid19. A software tool has also been developed so that interested parties can explore the proof-of-concept system.
DOI
10.1371/journal.pcbi.1008604
WOS
WOS:000612933300003
Archivio
http://hdl.handle.net/11368/2993761
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85100008159
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008604
Diritti
open access
license:creative commons
license uri:http://creativecommons.org/licenses/by/4.0/
FVG url
https://arts.units.it/bitstream/11368/2993761/1/Bin_el_al_PLOS_Computational_Biology_2021.pdf
Soggetti
  • COVID-19

  • switching control

Scopus© citazioni
39
Data di acquisizione
Jun 14, 2022
Vedi dettagli
Web of Science© citazioni
33
Data di acquisizione
Mar 19, 2024
Visualizzazioni
2
Data di acquisizione
Apr 19, 2024
Vedi dettagli
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