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Effect of the Janus kinase inhibitor tofacitinib in the treatment of juvenile scleroderma: A single-center experience

Colussi, Lara
•
Dagri, Arianna
•
Pastore, Serena
altro
Taddio, Andrea
2024
  • journal article

Periodico
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
Abstract
Juvenile scleroderma (JS) is a group of diseases characterized byincreased skin thickness and fibrosis. It is the third-most commonrheumatic condition in childhood. There are two major forms of thedisease: juvenile localized scleroderma (JLS) and juvenile systemicsclerosis (JSSc), both classified into different subtypes depending onthe extent of the disease and the depth of the lesions.1 JLS, alsoknown as morphea, affects only the skin and subdermal tissues,while JSSc also includes fibrous changes in internal organs such asthe esophagus, intestines, heart, lungs, and kidneys
DOI
10.1111/1756-185X.15295
WOS
WOS:001294636300001
Archivio
https://hdl.handle.net/11368/3096445
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85201645335
https://onlinelibrary.wiley.com/doi/10.1111/1756-185X.15295
Diritti
closed access
license:copyright editore
license uri:iris.pri02
FVG url
https://arts.units.it/request-item?handle=11368/3096445
Soggetti
  • Morphea

  • Scleroderma

  • Therapy

  • JAK inhibitor

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