Ex vivo Time Evolution of Thrombus Growth through Optical and Electrical Impedance data fusion

We designed a novel sensor specifically aimed at ex vivo measurements of white thrombus volume growth; a white thrombus is induced within an artificial micro-channel where hemostasis takes place starting from whole blood under flow conditions. The advantage of the proposed methodology is to identify the time evolution of the thrombus volume by means of an original data fusion methodology based on 2D optical and electrical impedance data simultaneously processed. On the contrary, the present state of the art optical imaging methodologies allow the thrombus volume estimation only at the end of the hemostatic process.