The article presents a research on development scenarios for intermodal transport between Italy and Eastern Europe. These scenarios are examined in the whole context of Northern Italy freight transport with particular reference to West-East (Torino-Milano-Verona-Venezia-Trieste) Corridor and UE Corridor V (Venezia-Trieste-Ljubljana-Budapest) and defined by Crete Conference in 1994. Existing links are examined both under the demand and the supply side. Development scenarios are related with economic perspesctives of North-Eastern and South-Eastern European countries. Consequent trends in freight intermodal transport are confronted with present networks, leading to a first definition of infrastructural needs.