This article focuses on the design and analysis of experiments with mixtures, very commonly involved in product development whenever a multicomponent system is concerned. Here, classical and computer-aided designs for mixture studies are introduced and discussed with various numerical examples. In fact, the strategies, which may be adopted by the experimenter for the construction of blending models in the region of interest, are quite different. The use of various methods and techniques for analysis and optimization are here illustrated by some case studies taken from practical experiences to analyse step by step the procedures adopted for the experimentation and the analysis of mixture data.