The LHC experiments have analyzed the 7 and 8 TeV LHC data in the main Higgs production and decay modes. Current analyses only loosely constrain an anomalous top-Higgs coupling in a direct way. In order to strongly constrain this coupling, the Higgs-top associated production is reanalyzed. Thanks to the large destructive interference in the t-channel for standard model couplings, this process can be very sensitive to both the magnitude and the sign of a non-standard top-Higgs coupling. We project the sensitivity to anomalous couplings to the integrated luminosity of 50 fb−1, corresponding to the data collected by the ATLAS and CMS experiments in 7 and 8 TeV collisions, as of 2012. We show that the combination of diphoton and multi-lepton signatures, originating from different combinations of the top and Higgs decay modes, can be a potential probe to constrain a large portion of the negative top-Higgs coupling space presently allowed by the ATLAS and CMS global fits.
