Neuroreceptors are involved in many neurological diseases and represent the preferential target
for the pharmacological treatments. Thus functional studies of their activity, by the use of electrophysiological
techniques, are a fundament approach to understand not only the pathological mechanism of many
neurological diseases but also the mechanism of action of potential drugs. Unfortunately, this cannot be
applied for studying the receptor activity in all the human tissues. The option is the use of animal models,
however they often resemble only some of the neurological diseases in human. In addition, adult or old
animals are not always suitable for electrophysiological studies of age-related diseases. Here, we propose the
microtransplantation technique as a novel and useful method to study receptors in humans and, more in
general, in adult animals.
