A 45-year-old man from Nigeria in generally good health presented with a giant occipital neoformation approximately 8 × 8 cm. The lesion, exophytic, ulcerated, bleeding, and foul-smelling, had first appeared 4 months earlier and had grown rapidly. There was another similar, smaller lesion near the original one, which was presumed to be an intransit metastasis. Contrast-enhanced computed tomography and positron emission tomography scans confirmed that the patient had already developed lung, bone, and kidney metastases.