The “in vitro” study of white thrombus growth by means of Electrical Impedance Spectroscopy on whole blood is presented; the aim of the work is to correlate thrombus formation in an artificial channel with impedance measurements. The measurement bench is composed of a sensor, a switch unit and an impedance meter. Post process of measured data is performed and an equivalent lumped circuit is derived; experimental data are obtained with a first prototype based on a single couple of electrodes.