Celiac patient-derived anti-transglutaminase 2
(TG2) antibodies disturb several steps in angiogenesis, but
the detailed molecular basis is not known. Therefore, we here
analyzed by microarray technology the expression of a set of
genes related to angiogenesis and endothelial cell biology in
order to identify factors that could explain our previous data
related to vascular biology in the context of celiac disease. To
this end, in vitro models using human umbilical vein endothelial
cells (HUVECs) or in vivo models of angiogenesis
were used.
