Efficient Cleavage of Carboxylic tert-Butyl and 1-Adamantyl Esters, and N-Boc-Amines using H2SO4 in CH2Cl2
STRAZZOLINI, Paolo
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POLESE, Pierluigi
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MISURI N
2005
Periodico
TETRAHEDRON LETTERS
Abstract
A new procedure for the deprotection of carboxylic tert-butyl and 1-adamantyl esters, and N-Boc-amines using H2SO4 in CH2Cl2 is described. The proposed method is simple, cheap, eco-friendly and represents a valid alternative to existing ones, with special significance in large scale applications. 2005 Elsevier Ltd. All rights reserved.
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