Transgender teenagers often experience discomfort related to their bodies, particularly concerning the chest and genital anatomy, which are among the elements leading to more severe incongruence. Non-medical interventions like binding and tucking are reversible, temporary practices that facilitate gender affirmation and can help alleviate discomfort before surgical interventions. Beyond the benefits for an individual’s mental health, these practices can also have long-term physical side effects, especially when not done correctly. Only a few studies have analyzed the risks and benefits of these practices, primarily among the adult population; there is still a lack of data in pediatrics. Given the increasing number of requests for care of transgender teenagers, there is a need for more in-depth study and intervention proposals. This work aims to compare some available data in literature to provide accurate information and helpful advice to teenagers who are using or want to try these tools.