In Italy CRC screening program invites people between 50 and 69 years to perform a biannual fecal occult blood test FIT and in individuals with a positive result a colonoscopy is offered. Data about how CRC screening is specifically conducted in Italy is currently lacking. The study of the existing discrepancies is a first necessary step to planning corrective measures to bridge the gap between current clinical practice and recommendations [5]. Therefore, the Scientific Committee of Federazione Italiana Società Malattie Apparato Digerente (FISMAD), a federation of Italian digestive disease associations, conducted a survey on CRC screening activities in Italy.