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Compartor: A toolbox for the automatic generation of moment equations for dynamic compartment populations

Pietzsch T.
•
Duso L.
•
Zechner C.
2021
  • journal article

Periodico
BIOINFORMATICS
Abstract
Many biochemical processes in living organisms take place inside compartments that can interact with each other and remodel over time. In a recent work, we have shown how the stochastic dynamics of a compartmentalized biochemical system can be effectively studied using moment equations. With this technique, the time evolution of a compartment population is summarized using a finite number of ordinary differential equations, which can be analyzed very efficiently. However, the derivation of moment equations by hand can become time-consuming for systems comprising multiple reactants and interactions. Here we present Compartor, a toolbox that automatically generates the moment equations associated with a user-defined compartmentalized system. Through the moment equation method, Compartor renders the analysis of stochastic population models accessible to a broader scientific community.
DOI
10.1093/bioinformatics/btab058
WOS
WOS:000697377500045
Archivio
https://hdl.handle.net/20.500.11767/145836
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85107866695
https://pubmed.ncbi.nlm.nih.gov/33538766/
https://ricerca.unityfvg.it/handle/20.500.11767/145836
Diritti
open access
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