Lymphoproliferative disorders are heterogeneous malignancy characterized by the expansion of a lymphoid clone more or less
differentiated. At the level of the oral cavity, the lymphoproliferative disorder can occur in various ways, most commonly as
lymphoid lesions with extranodal externalization, but sometimes, oral lesions may represent a localization of a disease spread.
With regard to the primary localizations of lymphoproliferative disorders, a careful examination of the head and neck, oral, and
oropharyngeal area is necessary in order to identify suspicious lesions, and their early detection results in a better prognosis for the
patient. Numerous complications have been described and frequently found at oral level, due to pathology or different therapeutic
strategies. These complications require precise diagnosis and measures to oral health care. In all this, oral pathologists, as well as
dental practitioners, have a central role in the treatment and long-term monitoring of these patients.
