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Bilitranslocase and anthocyanins role in the gastrointestinal tract

Čvorović, Jovana
•
Tramer, Federica
2014
  • Controlled Vocabulary...

Abstract
Bilitranslocase (BTL) is a organic anion transporter expressed in liver and in several extra-hepatic tissues. This membrane protein transports different substrates as pyrrolic molecules, nucleotides, flavonoids. Anthocyanins, one of the most represented flavonoids class are known to have antioxidant activity. They act as anti-inflammatory, anti-cancer and anti-proliferative molecules by interfering with different intracellular pathways. Some chronic colon diseases results in an increase in the pro-inflammatory machinery that are associated with a 5-fold increased risk of developing colon cancer. The expression and the role of BTL in the gastrointestinal tract in normal and pathological condition, as well as its role as anthocyanins transporter in colon cancer cells will be take into account in Trans2care project.
Archivio
http://hdl.handle.net/10077/10045
Diritti
open access
Soggetti
  • bilitranslocase

  • organin transporter

  • flavonoids

  • anthocyanins

  • colon cancer

  • chronic colon disease...

Visualizzazioni
1
Data di acquisizione
Apr 19, 2024
Vedi dettagli
google-scholar
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