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Carotid aneurism with acute dissection: An unusual case of IgG4-related diseases

Barp A.
•
Fedrigo M.
•
Farina F. M.
altro
Angelini A.
2016
  • journal article

Periodico
CARDIOVASCULAR PATHOLOGY
Abstract
Aim: IgG4-related disease is a systemic disease that involves organs and vascular structures, in particular, the aorta. This is the first case that showed the carotid artery involvement with dissection evolution. Methods and Results: In a 67-year-oldman with speech impairment and right-hand clumsiness, a brain computed tomography revealed signs of acute ischemia in the left frontal lobe while an echo-color Doppler sonography of the cervical vessels showed a tight stenosis of left internal carotid artery with a large pseudoaneurysm. Histological findings performed on the surgical specimen disclosed IgG4-related disease. Conclusions: To the best of our knowledge, this is the first manifestation of IgG4-related disease with carotid artery dissection complicated by pseudoaneurysm. Even though unsuccessful since the patients died within 48 h, this case highlights the diverse facets of the IgG4-related disease representing a new complication with important clinical implications of such a diagnosis targeting immunosuppressive therapy particularly B-cell depletion.
DOI
10.1016/j.carpath.2015.08.006
WOS
WOS:000369718900010
SCOPUS
2-s2.0-84951733301
Archivio
http://hdl.handle.net/11368/2953739
https://www.sciencedirect.com/science/article/pii/S1054880715001064?via=ihub
Diritti
closed access
FVG url
https://arts.units.it/request-item?handle=11368/2953739
Soggetti
  • Carotid dissection

  • IgG4-related disease

Web of Science© citazioni
12
Data di acquisizione
Jun 8, 2022
Scopus© citazioni
13
Data di acquisizione
Jun 14, 2022
Vedi dettagli
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