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Gene expression profiling in breast cancer: A clinical perspective

Arpino, Grazia
•
GENERALI, DANIELE
•
Sapino, Anna
altro
Dogliotti, Luigi
2013
  • journal article

Periodico
THE BREAST
Abstract
Gene expression profiling tests are used in an attempt to determine the right treatment for the right person with early-stage breast cancer that may have spread to nearby lymph nodes but not to distant parts of the body. These new diagnostic approaches are designed to spare people who do not need additional treatment (adjuvant therapy) the side effects of unnecessary treatment, and allow people who may benefit from adjuvant therapy to receive it. In the present review we discuss in detail the major diagnostic tests available such as MammaPrint dx, Oncotype dx, PAM50, Mammostrat, IHC4, MapQuant DX, Theros-Breast Cancer Gene Expression Ratio Assay, and their potential clinical applications
DOI
10.1016/j.breast.2013.01.016
SCOPUS
2-s2.0-84875534675
Archivio
http://hdl.handle.net/11368/2903843
Diritti
metadata only access
Soggetti
  • Breast cancer

  • Gene arrays

  • Gene profiles

  • Prognostic factors

  • Surgery

Web of Science© citazioni
50
Data di acquisizione
Jun 5, 2022
Scopus© citazioni
56
Data di acquisizione
Jun 14, 2022
Vedi dettagli
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