Ruolo
Docenti di ruolo di Ia fascia
Qualifica (ricerca)
Professori Ordinari
 
Area Ministeriale
AREA MIN. 05 - Scienze biologiche
Macro-settore concorsuale
05/E - BIOCHIMICA E BIOLOGIA MOLECOLARE SPERIMENTALI E CLINICHE
Settore SSD
Settore BIO/11 - Biologia Molecolare
Short CV

PERSONAL DATA. Born in Trieste, Italy in 1959. Married with two children. EDUCATION. 1984, Degree in Medicine; University of Trieste, Italy. 1989, Ph.D. in Microbiology and Virology; University of Genoa, Italy. POSITIONS. Since 2004, Director of the Italian Component of the International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy; coordination of 17 research groups, over 210 people from 29 different countries (www.icgeb.org). From 2000-2004, Founder and first Director of the Molecular Biology Laboratory of the Scuola Normale Superiore in Pisa, Italy. From 1995-2000, Senior Scientist and Group Leader, ICGEB Trieste. TEACHING. Since 2005, Full Professor of Molecular Biology at the Faculty of Medicine of the University of Trieste. From 2000 to 2005, Associate Professor of Molecular Biology at the Scuola Normale Superiore in Pisa, Italy. REVIEWER ACTIVITY. Reviewer for over 30 peer-reviewed international journals in the fields of gene therapy, cardiovascular disorders and HIV infection and for several grant applications in the context of national and international calls. SCIENTIFIC INTERESTS. Current research interests focus on the identification of novel gene or cell therapy strategies for the treatment of cardiovascular disorders. SCIENTIFIC ACTIVITY. Published over 250 full papers, with over 200 in peer-reviewed international journals, including Nature Medicine, Science, Molecular Cell, the Journal of Clinical Investigation, and others. SEMINARS AND INVITED LECTURES. Over the last few years, invited to present his research activity at over 100 seminars in Universities and Research Institutions in the United States, Europe, Japan and Australia. FUNDING. Since 2010, he has been the recipient of a ~2 million Euro Advanced Grant from the European Research Council (ERC). Over the last several years, he has obtained grants for his research activity from various other public and private bodies. Further info: http://www.icgeb.org/...

PERSONAL DATA. Born in Trieste, Italy in 1959. Married (Serena Cividin) with two children (Massimo, 23 and Giovanna, 12). EDUCATION. 1984, Degree in Medicine; Faculty of Medicine, University of Trieste, Italy. 1985, Professional License; Admitted to the Medical Doctors and Surgeons Register, University of Bologna Medical School. 1989, Ph.D. in Microbiology and Virology; University of Genoa, Italy. POSITIONS. Since 2004, Director of the Italian Component of the International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy; coordination of 17 research groups, over 210 people from 29 different countries (www.icgeb.org). Since 1995, Group Leader of the Molecular Medicine Laboratory at ICGEB Trieste; supervision of over 25 scientists and technicians. From 2000-2004, Founder and first Director of the Molecular Biology Laboratory of the Scuola Normale Superiore in Pisa, Italy, one of the leading academic institutions in Italy. From 1995-2000, Senior Scientist and Group Leader, ICGEB Trieste. From 1990-1994, Staff Scientist, ICGEB Trieste. 1985-1989, PhD student, Istituto di Genetica Biochimica ed Evoluzionistica, National Research Council (CNR), Pavia, Italy OTHER APPOINTMENTS AND PROFESSIONAL MEMBERSHIPS. Since 2005, member of the Scientific Council of the National Center for Genetic Engineering and Biotechnology (BIOTEC) of Bangkok, Thailand. From 2001-2005, member of the Executive Committee of NEST (National Enterprise for NanoScience and NanoTechnology) at the Scuola Normale Superiore in Pisa, Italy. Since 1998, member of the Ethical Committee of the University Hospital, Trieste, Italy. Since 1996, Consultant, member of the evaluation committees for various grant programs of the Italian Ministry for Instruction, University and Research (MIUR), Italy and of the National Council for Research (CNR), Italy. Since 1996, Scientific consultant for the Italian Association for the Prevention and Cure of Handicaps (AIRH). 1995-1997: Member of the Scientific Board of the Italian Society of Molecular Biology and Biophysics (SIBBM). HONORS. 1993: TOYP (To-the-Outstanding Young Person) Prize for scientific Research, Junior Chamber Italy. 2007: Lenghi-Magrassi International prize for outstanding research in virology, Accademia Nazionale dei Lincei TEACHING. Since 2005, Full Professor of Molecular Biology at the Faculty of Medicine of the University of Trieste. From 2000 to 2005, Associate Professor of Molecular Biology at the Scuola Normale Superiore in Pisa. Member of the Faculty of PhD Schools at the University of Trieste, University of Turin, Scuola Normale Superiore in Pisa and the International School for Advanced Studies (SISSA) in Trieste, Italy. SUPERVISING ACTIVITY. Over the last 15 years he has directly supervised the research activity of more than 25 post-docs, and more than 30 PhD students, from the Open University UK, the Scuola Normale Superiore (Pisa, Italy) and the International School for Advanced Studies (ISAS, Trieste, Italy). From 2000 to 2004 he has been responsible for all the activities – including the overall supervision of students – of the PhD course in Molecular Biology of the Scuola Normale Superiore in Pisa, Italy. He has served as external examiner at the University of Coimbra, Portugal and the University of Montpellier, France. REVIEWER ACTIVITY. Reviewer for over 30 peer-reviewed international journals in the fields of gene therapy, cardiovascular disorders and HIV infection, including The Lancet, Gene Therapy, Cancer Gene Therapy, Molecular Therapy, Circulation, Circulation Research, the EMBO Journal, Blood, Journal of Biological Chemistry, Journal of Virology, Retrovirology, Journal of Cell Science, American Journal of Pathology, Journal of Hepatology, Nucleic Acids Research, FASEB J and others. Over the last 15 years, he has reviewed several grant applications in the context of calls from the European Commission (FP6 and FP7), the Ministry of University of Research of Italy, the Istituto Superiore di Sanita' of Italy, the Telethon Foundation Italy, the Philip Morris Research Foundation and various institutions in France, UK, Slovenia, The Netherlands and Spain. SCIENTIFIC INTERESTS. His current research interests focus on two major topics in the field of Molecular Medicine. The first project concerns the development of viral vectors for human gene therapy, with special emphasis on vectors based on the adeno-associated virus (AAV) and their application for gene therapy of cardiovascular disorders. The ultimate purpose of these studies is the induction of new blood vessel formation and cardiac regeneration in patients with myocardial infarction or heart failure. The second project concerns several aspects of the molecular biology of HIV-1 infection with particular reference to the study of the interactions of some viral proteins (Tat, integrase) with cellular factors. SCIENTIFIC ACTIVITY. He has published over 250 full papers, with over 200 in peer-reviewed international journals, including, Science, Nature Medicine, Molecular Cell, the Journal of Clinical Investigation, Nature Structural and Molecular Biology, the EMBO Journal, the Proceedings of the National Academy of Science of the USA, Journal of Biological Chemistry, Circulation Research, the Journal of Virology, the American Journal of Human Genetics, Molecular and Cellular Biology, Molecular Therapy and others; 20 reviews or chapters in published books and university text books. He has participated in over 250 scientific meetings, more than 200 of which at the international level. Over 300 communications on his research activity have been presented. He regularly contributes articles to national newspapers and popular science magazines. SEMINARS AND INVITED LECTURES. Over the last few years, he has been invited to present his research activity at over 100 seminars in Universities and Research Institutions in the United States, Europe, Japan and Australia, including Harvard University, Stanford University, New York Medical College, Valhalla, New York and NIAID-LMM at NIH Bethesda, USA, the Wellcome/CRC Institute in Cambridge, the University of Oxford, Oxford, UK, the University of Munich, Germany, the University of Tokyo, Japan, the University of Queensland, Brisbane, Australia, the University of Maastricht, The Netherlands, the “Institut de Génétique Humaine”, Montpellier and the “Institut Pasteur”, Paris France, the Vienna Biocenter, Vienna, Austria, in addition to numerous Italian Universities. FUNDING. Since 2010, he has been the recipient of a ~2 million Euro Advanced Grant from the European Research Council (ERC). Over the last several years, he has obtained grants for his research activity from various public and private bodies, including the European Union, the Italian Ministry for Education and Research (MIUR, PRIN and FIRB projects), the World Antidoping Agency (WADA), Montreal, Canada, the Ataxia UK Charity, UK, the Consiglio Nazionale delle Ricerche (CNR), Italy, the Italian Association for Cancer Research (AIRC), Italy, the Telethon foundation Italy, the Istituto Superiore di Sanita' Italy, various Bank Foundations, the Regional Government of Friuli-Venezia Giulia, Italy, and others. Further information: http://www.icgeb.org/mauro-giacca.html

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